Recycle your burden of Oxidized Glutathione in the original Thioguard Lotion™, now also offered with additional methylcobalamin (methylB12), providing even greater support for those seeking to enhance methylation. Suitable for those using thioguard and as alternative to Methlycobalamin Injections. 
 
With the addition of methylcobalamin, our advanced formula offers support crucial for numerous biological processes. Methylcobalamin, a bioactive form of vitamin B12, plays a vital role in supporting neurological, nervous, and immune system functions, further enhancing the effectiveness of Thioguard Lotion™ in these areas:
 
Support for Sulfation
Support For Cellular Rhodanese
Enhanced Topical Delivery
Access a large surface area of cells topically to quickly reduce the oxidized burden and support the body's conversion of Inactive B12 to Active B12.
Comprehensive Support for Cellular Processes
 
Oxidized glutathione (GSSG) is the disulfide form of the antioxidant glutathione (GSH). It plays a role in maintaining the redox balance within cells. GSSG can act as a reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger, but it can also exert inhibitory effects on certain enzymes, including SAM synthetase.
 
The inhibition of SAM synthetase by GSSG occurs due to the disulfide bond present in GSSG. The disulfide bond can react with and modify critical cysteine residues within the active site of SAM synthetase, thereby disrupting its enzymatic activity.
 
This inhibition can have significant consequences since SAM is involved in numerous methylation reactions that are essential for cellular processes, including DNA and protein methylation, neurotransmitter synthesis, and detoxification reactions. Impairment of SAM synthetase activity can disrupt these processes and have a broad impact on cellular function.
 
Supporting your cellular processes to convert GSSG to GSH reduces the methylation-inhibiting oxidized glutathione burden and provides new glutathione for use. With the addition of methylcobalamin, Thioguard Lotion™ now offers additional methylation support, enhancing the body's ability to perform these vital functions.
 
Additional Benefits with Methylcobalamin
 
Support for mood improvement and stabilization
Supports enhanced mental focus and concentration
Supports improved organization skills
Supports individuals with MTHFR variations
Supports addressing short-term memory loss
Promotes a healthy sleep cycle
Supports immune function and overall well-being
 
Experience the combined benefits of glutathione support and the enhanced methylation capabilities of methylcobalamin with our Thioguard Lotion™. Empower your health and well-being with our scientifically advanced, topically applied solution.